FamilyNeisseriaceae
By:Prof. Dr.Moussa
CommensallyNeisseriaare present in:
ConjunctivaThroatMucous membraneRectum, cervix and uterus.
PathogenicNeisseriaare:
Neissseriameningitides.N. gonorrhea.
PathogenicNeisseria
Morphology:Gram –veDiplococcic – kidney shapeNon-motileNon-sporulatedCapsulatedHabitat:N . meningitis → carried in nasal pharynxN. gonorrhea→ no carrier, if present considered patient
Culture
Can’t grow in N. agar orMacconkeyThey are fastidious microorganism (Need blood to grow) best chocolate agar.The selective media for isolation of pathogenicNeisseria→Thayer Martin Medium → (chocolate agar + antibiotic VCN)vancomycinColistinNystatinGrow at 37°C after 24hr aerobically.Non hemolyticNeed CO2(5-10%)
What is gonorrhea?
It is venereal disease (sexually transmitted)Acute :male → severe urethral discharge .Female → Cervical discharge .Chronic :Male →morning drops of pus andorchitislead to sterility & systemic infection .Female →inflammation of fallopian tubes (salpingitis)Inflammation of ovary (oophoritis).Cervical discharge.AntibioticColistinresistance
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