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CLEAN TAVI Summary Slide

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CLEAN-TAVI
At 2 days, there was a significant reduction in the total number of lesions on MRI in the CEPD vs. nofilterarms: 8vs. 16,p = 0.0023Similar results were noted on 7-dayMRI: 5vs. 10,p = 0.012Clinical strokes were similar
Trial design:Patientsundergoing TAVR were randomized in 1:1 fashion to receive either a cerebral embolicprotectiondevice (CEPD), Claret-Montage,or routinemanagement during the procedure. Patientswere followed for7 days.
Results
Conclusions
Presented byDr. AxelLinkeatTCT 2014


CEPD(n= 50)
Total lesions on MRI at 48 hours
Embolicprotectionwith Claret-MontageCEPD results in fewer cerebral embolic eventsvs. routinemanagement using no filter intransfemoralTAVR; resultsare interesting given the high cerebral embolism rate inTAVRpatientsFurtherstudies powered for clinical endpoints in TAVR patients are necessary
No filter(n =50)
No. of lesions
(p=0.0023)

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CLEAN TAVI Summary Slide